Validation & Scalability

How do you guarantee scalable production volume and a validated process?shutterstock_21104719

Greaves has the knowledge and expertise to succeed

To deliver at a guaranteed high standard to multiple customers relies on two pivotal factors:

  • The knowledge and equipment to meet a wide spectrum of different needs, ranging from small-volume lab testing to full-scale mass production
  • The ability to switch between these varying processes cleanly and efficiently.

Joshua Greaves & Sons Ltd is perfectly placed to work with manufacturers to achieve the best possible results on both counts.

Consistency. From Lab…

“Scalable, flexible machines are the hot topic,” says Sales Director Edward Greaves. “Faultless, pinpoint accuracy, whatever the scale, with reliable validation at every stage, is critical to the success of this kind of multi-product, high-volume manufacturing. The exact requirements of each product for each client must be guaranteed.

…to volume production

Greaves has extensive experience in a key area where extreme precision is paramount; We know how to design and build mixers that operate consistently to very tight specification and tolerance”.

All models of Greaves mixers are available from Laboratory to pilot scale through to lower then high volume manufacture. Greaves are ahead of the game in incorporating the key design elements including:

  • Impeller geometry
  • Impeller-to-tank-diameter ratios
  • Flow rates
  • Peripheral speeds
  • Vacuum pressure

The balance and relationship between each of these factors is crucial for achieving the desired levels of consistent scalability.
Greaves also understands importance of matching the best speed with pharmaceutical-grade thoroughness in cleaning machinery after its use in one production process as the same equipment is prepared for a new production run. Every minute of unnecessary downtime in the site operation costs money but avoiding any risk of cross-contamination is essential.

In our drive to deliver end-to-end mixer performance, Greaves has used our expertise in machinery design to develop PortaCIP the ultimate, portable clean in-place system. The PortaCIP system practically addresses the real-world implications design factors including:IMG_7604DoubleBallCoverage_Diagram

  • Nozzle flexibility
  • Area coverage
  • Vessel geometry
  • Internal surface roughness,
  • Crevices and residue traps (including) nuts, bolts and securing devices.

Ever aware of the importance of cost-efficiency, PortaCIP also includes a system for the efficient use and reuse of cleaning fluids

To get the best from your mixer investment, call us.